Phenylboronic acid, CAS 98-80-6, is an organoboron building block used mainly in carbon–carbon coupling, pharmaceutical intermediate synthesis, agrochemical research, and other specialty chemical applications. Its molecular formula is C6H7BO2, and its molecular weight is approximately 121.93 g/mol. For most buyers, the right purchasing decision depends on more than the chemical name: purity, analytical documentation, packaging, moisture control, delivery requirements, and intended reaction use should all be reviewed before an order is confirmed.
At Maison Chemical, I help B2B customers evaluate Phenylboronic Acid CAS 98-80-6 according to their process requirements rather than treating every inquiry as a standard commodity purchase. This guide explains what the material is, how it is used, which specifications matter, and how buyers can reduce sourcing risk when requesting a quotation.
This guide is intended for research organizations, pharmaceutical intermediate manufacturers, chemical distributors, formulation developers, procurement teams, and process chemists sourcing phenylboronic acid in commercial quantities. It is also relevant to buyers who need to compare suppliers for laboratory, pilot-scale, or recurring production use. The appropriate specification may differ considerably between an exploratory reaction and a regulated manufacturing process.
Buyers should use this information as a sourcing framework, then confirm the final requirements against their own reaction protocol, quality system, safety procedures, and applicable regulations. A supplier quotation should be based on a clear written specification instead of only the CAS number.
Phenylboronic acid is an aromatic boronic acid containing a phenyl group attached to a boronic acid functional group. In organic synthesis, the boron-containing group can participate in palladium-catalyzed Suzuki–Miyaura coupling with suitable aryl or vinyl halides, providing a practical route to biaryl and related structures. Its reactivity makes it a valuable intermediate rather than simply a general-purpose solvent or additive.
The compound is commonly handled as a solid chemical raw material. Its behavior can be affected by storage conditions, moisture exposure, particle form, and the age of the material, so buyers should review the supplier’s storage guidance and analytical documentation. I recommend confirming appearance, assay method, water content where relevant, and impurity controls before approving a source.
Phenylboronic acid is frequently selected as a building block for the preparation of substituted aromatic compounds. In pharmaceutical intermediate routes, it can provide a phenyl fragment during a coupling step, although actual suitability depends on the substrate, catalyst system, solvent, base, temperature, and purification process. The material should therefore be qualified within the customer’s specific synthetic route.
The same carbon–carbon coupling chemistry supports the development of agrochemical intermediates and specialty molecules containing aromatic structures. Research teams may use phenylboronic acid during route scouting, analogue preparation, or process development. In these applications, consistent assay and predictable impurity profiles can be more important than selecting the lowest nominal price.
Boronic acids can interact reversibly with compounds containing suitable diol or polyol structures under appropriate conditions. This chemistry has been investigated in sensing, separation, and functional materials research, although the exact performance depends on pH, solvent, molecular design, and application conditions. Buyers should avoid assuming that a material grade intended for synthesis automatically meets the requirements of a specialized materials or analytical project.
The CAS number identifies the substance, but it does not define every commercial quality requirement. Before purchasing, I suggest requesting a current specification sheet and Certificate of Analysis for the proposed lot. The documents should be reviewed against the customer’s internal acceptance criteria, particularly when the product will enter a multi-step manufacturing process.
| Specification Area | What to Confirm | Why It Matters |
|---|---|---|
| Identity | CAS 98-80-6, chemical name, formula, and identification method | Confirms that the quoted material matches the requested substance |
| Assay or purity | Target purity, analytical method, and reported impurity profile | Supports reaction consistency and downstream process control |
| Physical description | Appearance, color, particle form, and packaging condition | Helps with handling, sampling, and production planning |
| Moisture and related controls | Water content or other parameters required by the process | Some reactions and storage systems are sensitive to moisture |
| Documentation | COA, SDS, specification sheet, and shipping documents | Supports quality review, logistics, and safe handling |
Commercial grades may be offered at different purity levels, such as 98% or higher, but the exact value, test method, and batch result must be confirmed with the supplier. A stated purity percentage is meaningful only when the analytical basis is clear. I also recommend asking whether the quoted value is a release specification, a typical result, or a result from the specific lot available for shipment.
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Start by stating whether the material is for laboratory research, process development, pilot production, or commercial manufacturing. Specify the target reaction or product when possible, because the required impurity control may depend on the chemistry that follows. Also indicate whether the material will be used directly or converted into another intermediate before purification.
Define the minimum assay, appearance requirements, moisture expectations, and any restricted impurities. If your process uses sensitive catalysts or requires a narrow impurity profile, provide those requirements before receiving a quotation. This allows the supplier to recommend an appropriate grade instead of offering a technically unsuitable standard item.
Ask how the product is packed for the requested quantity and whether smaller inner packages are available. Packaging should protect the material during storage and transport while supporting safe opening and sampling at the destination. The buyer should also confirm the recommended storage conditions, shelf-life information, and any special handling instructions before purchase.
Lead time is affected by stock status, quantity, packaging, testing, export procedures, and destination requirements. A supplier may be able to provide a faster response for an available lot than for a made-to-order quantity, but this should be confirmed in writing. Request the COA and SDS review process early, especially if your company requires quality approval before shipment.
The price of Phenylboronic Acid CAS 98-80-6 is influenced by purity, order volume, packaging, testing requirements, production schedule, and shipping destination. A lower unit price may not represent the lowest total procurement cost if it requires additional testing, repacking, or a longer release process. I recommend comparing quotations on a delivered and documented basis rather than looking only at the price per kilogram.
Minimum order quantity can vary by supplier and grade. For an initial qualification, buyers may request a development quantity or sample-size package, while recurring production may justify a larger purchase plan. Lead time should be separated into production time, quality-release time, and transportation time so that the project schedule reflects the complete supply cycle.
At Maison Chemical, I support B2B inquiries by reviewing the requested grade, quantity, packaging, destination, and documentation needs before preparing a quotation. Depending on the project, our support can include specification clarification, COA and SDS coordination, packaging discussion, shipment planning, and communication about recurring supply requirements. The exact availability, commercial terms, and quality documents should be confirmed for each order and lot.
One common mistake is ordering solely by CAS number without defining purity or documentation requirements. Another is assuming that a laboratory pack and a production pack have identical packaging, release procedures, or delivery conditions. Buyers should also avoid approving a supplier based only on a typical specification when their own process requires lot-specific testing.
It is also important not to treat phenylboronic acid as interchangeable with other boronic acids without reviewing the reaction route. Substituent effects, solubility, steric properties, and downstream purification behavior can change substantially between materials. If a substitute is being considered, it should be evaluated through documented technical review and suitable process testing.
The best way to source Phenylboronic Acid CAS 98-80-6 is to begin with the application, define the required quality profile, and then compare suppliers on documentation, packaging, delivery capability, and technical communication. The CAS number confirms the requested substance, but it does not replace a complete purchasing specification. For pharmaceutical intermediate and specialty chemical projects, a clear lot-specific quality review can help reduce avoidable production and qualification risks.
If you are evaluating Phenylboronic Acid CAS 98-80-6, send Maison Chemical your required purity, quantity, packaging preference, destination, and documentation requirements. I can help organize the inquiry into a practical B2B quotation request and confirm the available supply options, commercial terms, and supporting documents for your project.
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