Side Effects of Hyalgan (Hyaluronate), Warnings, Uses

Hyalgan Side Effects Center

What Is Hyalgan?

Hyalgan (sodium hyaluronate) is a synovial fluid replacement that works by acting as a lubricant and shock absorber in the joint used to treat knee pain in patients with joint inflammation (osteoarthritis). Hyalgan is usually used in patients who have not responded to other treatments such as acetaminophen, exercise, or physical therapy.

What Are Side Effects of Hyalgan?

Common side effects of Hyalgan include:

• injection site reactions (pain, swelling, redness, warmth, bruising, stiffness, or puffiness),
• headache,
• nausea,
• stomach pain,
• back pain,
• numbness or tingly feeling,
• cold symptoms (stuffy nose, sneezing, sore throat),
• tired feeling, or
• itching or skin irritation around the knee.

Tell your doctor if you have serious side effects of Hyalgan including:

• severe headache,
• fast or pounding heartbeat, or
• fever.

Seek medical care or call 911 at once if you have the following serious side effects:

• Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
• Serious heart symptoms such as fast, irregular, or pounding heartbeats; fluttering in your chest; shortness of breath; and sudden dizziness, lightheartedness, or passing out;
• Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors.

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

Dosage for Hyalgan

Hyalgan is given by intramuscular (IM) injection. A treatment cycle consists of a dose of five injections, given at weekly intervals.

What Drugs, Substances, or Supplements Interact with Hyalgan?

Hyalgan may interact with other drugs. Tell your doctor all medications and supplements you use.

Hyalgan During Pregnancy or Breastfeeding

During pregnancy, Hyalgan should be used only when prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

Additional Information

Our Hyalgan (sodium hyaluronate) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.