Carboxymethyl cellulose (CMC) or cellulose gum is a cellulose derivative with carboxymethyl groups (-CH2-COOH) bound to some of the hydroxyl groups of the glucopyranose monomers that make up the cellulose backbone. Carboxymethylcellulose, Sodium Salt is the most often used form of cellulose gum. CMC is used in a variety of industries as a thickener and/or to prepare stable emulsions in both food and non-food products. Insoluble microgranular CMC is used as a cation-exchange resin in ion-exchange chromatography for purification of proteins. Carboxymethyl cellulose has also been used extensively to characterize enzyme activity from endoglucanases (part of the cellulase complex).
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