4-Propylphenylboronic acid, CAS 134150-01-9, is an aryl boronic acid used primarily as a building block in organic synthesis, medicinal chemistry, and research-scale development. Its para-propyl-substituted phenyl group provides a hydrophobic organic fragment, while the boronic acid group enables carbon–carbon bond formation, especially in Suzuki–Miyaura coupling reactions. The compound has the molecular formula C9H13BO2 and a calculated molecular weight of approximately 164.01 g/mol. For B2B purchasing, I recommend evaluating identity, assay, impurity profile, packaging, documentation, and supply continuity together rather than selecting only by CAS number.
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This guide is intended for pharmaceutical and agrochemical research teams, contract development and manufacturing organizations, specialty chemical distributors, academic laboratories, and procurement professionals sourcing organic boronic acids. It is also useful for buyers comparing catalog material with project-specific or recurring supply. The information focuses on practical identification, application fit, quality review, and supplier communication. Final suitability should always be confirmed through the buyer’s own technical assessment and applicable process requirements.
4-Propylphenylboronic acid is an aryl boronic acid in which a propyl group occupies the para position of a phenyl ring relative to the boronic acid functionality. The boronic acid group is the key reactive feature because it can participate in transition-metal-catalyzed cross-coupling with suitable aryl or vinyl halides and related electrophiles. The propyl substituent can also influence the hydrophobic character and steric environment of the resulting molecule.
In practical synthesis, this material is normally treated as an organic intermediate rather than as a finished active ingredient or performance additive. Its role is to transfer the substituted aryl fragment into a larger molecular structure. Because boronic acids may be sensitive to moisture, oxidation, and storage conditions depending on the surrounding formulation and packaging, buyers should request handling and stability information relevant to the supplied batch.
| Parameter | Reference information | Purchasing significance |
|---|---|---|
| Product name | 4-Propylphenylboronic acid | Confirms the intended substituted aryl boronic acid |
| CAS number | 134150-01-9 | Primary identifier for sourcing and documentation |
| Molecular formula | C9H13BO2 | Supports structure and analytical review |
| Calculated molecular weight | Approximately 164.01 g/mol | Required for reaction calculations and inventory planning |
| Chemical class | Aryl boronic acid | Indicates likely use in cross-coupling and related synthesis |
The molecular formula and molecular weight are useful for checking a supplier quotation, certificate of analysis, and reaction documentation. However, these values alone do not prove batch quality or confirm the physical form. I advise buyers to compare the stated structure with analytical data such as proton and carbon NMR, mass spectrometry, chromatographic purity, and water content when those tests are relevant to the application.
Commercial aryl boronic acids are commonly supplied as solid laboratory or production intermediates, but appearance, particle size, and flow behavior may vary by manufacturing and packing process. A buyer should not treat a generic description such as “white powder” as a complete specification. The certificate should identify the lot, test method, assay or chromatographic purity, and any additional parameters agreed during quotation.
Storage should follow the supplier’s label and safety documentation. A controlled, dry environment and a tightly closed container are commonly considered prudent for moisture-sensitive organic intermediates, but the exact storage recommendation should be confirmed for the specific product. Handling must also follow the applicable Safety Data Sheet, internal chemical hygiene procedures, and local regulations.
The principal synthetic value of 4-propylphenylboronic acid is its use as a coupling partner for constructing biaryl, heteroaryl–aryl, and other carbon–carbon linked structures. In a typical Suzuki–Miyaura reaction, the aryl boronic acid is combined with an appropriate halide or pseudohalide in the presence of a suitable catalyst and base. The exact conversion, selectivity, and work-up requirements depend on the reaction partners, catalyst system, solvent, temperature, and scale.
This intermediate can be considered when a target molecule requires a para-propylphenyl fragment. It may be relevant to medicinal chemistry libraries, lead-optimization programs, specialty intermediates, and process research where structural diversification is needed. It should not be assumed to perform identically across all substrates, so screening and process-specific validation remain necessary.
In discovery chemistry, small quantities may be used to prepare analogues for structure–activity relationship studies. In process development, the focus generally shifts toward reproducible assay, impurity control, reaction robustness, filtration behavior, and scalable packaging. For commercial or regulated projects, buyers may also require traceability, change-control communication, and a defined documentation package.
Start by confirming the name, CAS number, molecular formula, and intended para-substituted structure. Similar names can refer to different positional isomers, such as 2-propylphenylboronic acid or 3-propylphenylboronic acid, which may give different reaction outcomes. If the material will enter a regulated or tightly controlled process, include a structure drawing or SMILES in the internal purchasing record.
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Specify whether the project needs research-grade material, high-purity intermediate, or a custom quality profile. Useful requirements may include minimum assay, maximum levels for specific related substances, residual solvents, water, inorganic residues, and metals. For a coupling reaction, the most important impurity limits may differ from those required for a downstream pharmaceutical intermediate, so the specification should be linked to the actual process.
Before ordering, request a current specification sheet and a representative or batch-specific certificate of analysis. Depending on the project, additional documents may include an SDS, non-animal-origin statement, residual solvent information, elemental impurity data, and packaging details. I recommend confirming which documents are available before issuing a purchase order, rather than assuming that every supplier provides the same package.
Quantity planning should reflect the intended stage of development. A small sample may be suitable for route screening, while kilogram-level requirements require greater attention to batch consistency, container configuration, transport conditions, and replenishment timing. Ask whether the quoted material is from existing stock, scheduled production, or a new manufacturing campaign because these options can affect lead time and documentation.
| Selection factor | Questions to ask |
|---|---|
| Identity | Does the documentation clearly match CAS 134150-01-9 and the para-propyl structure? |
| Purity | What analytical method is used, and are related substances reported? |
| Moisture and stability | Are water content, storage conditions, and retest guidance available? |
| Packaging | Is the container suitable for the requested quantity and transport route? |
| Supply continuity | Can the supplier support repeat orders and communicate changes? |
| Commercial terms | Are MOQ, sample availability, lead time, payment, and shipping terms clear? |
Price should be evaluated alongside usable quality and supply risk. A lower unit price may not be advantageous if the material requires additional purification, arrives with incomplete documentation, or cannot be replenished when a project advances. Buyers should compare quotations on an equivalent basis, including purity specification, package size, analytical support, delivery terms, and any requested custom testing.
One common mistake is selecting by chemical name alone without checking the CAS number and positional isomer. Another is requesting “high purity” without defining the analytical method or impurity limits. Buyers can also underestimate the importance of packaging and storage instructions when the material will be held for several months or transported across borders.
It is also risky to assume that a small research sample and a larger production lot will have identical analytical profiles without verification. If scale-up is likely, ask early about batch size, manufacturing continuity, sample retention, and change notification. These questions help reduce avoidable delays during route development or qualification.
At Maison Chemical, I support B2B buyers evaluating 4-Propylphenylboronic acid CAS 134150-01-9 for research, development, and commercial sourcing. We can discuss the required quantity, target specification, packaging preference, destination, and documentation needs before preparing a quotation. Product availability, MOQ, lead time, and export arrangements should be confirmed for each inquiry because they may vary by batch and order scope.
Our practical approach is to align the offered material with the customer’s intended use rather than provide a generic quotation only. When a project requires additional information, buyers can identify the required analytical tests or documents during the inquiry stage. This allows the purchasing and technical teams to review product fit before committing to a larger order.
4-Propylphenylboronic acid CAS 134150-01-9 is an aryl boronic acid intermediate with a calculated molecular weight of approximately 164.01 g/mol and a clear application focus in carbon–carbon bond-forming chemistry. Its suitability depends on more than identity: assay, related substances, moisture control, documentation, packaging, and supply continuity should all be reviewed. The most reliable sourcing process begins with a defined specification and a supplier capable of discussing both technical and commercial requirements.
For your next step, prepare the required quantity, target purity, intended application, destination, and documentation list. Contact Maison Chemical to confirm current availability, MOQ, lead time, packaging, and quotation terms for your project. We can then help you determine whether the available 4-Propylphenylboronic acid material matches your purchasing and process requirements.
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