4-Hydroxyphenylboronic acid CAS 71597-85-8 is an aromatic boronic acid used mainly as a synthetic building block in organic and medicinal chemistry. I identify it by its CAS Registry Number 71597-85-8, molecular formula C6H7BO3, and commonly listed molecular weight of approximately 137.93 g/mol. Its structure contains both a boronic acid group and a para-hydroxyphenyl group, allowing it to participate in carbon–carbon bond-forming reactions while also providing a phenolic functional group for further chemical modification.
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For B2B buyers, the most important point is that this material is generally purchased as a research, process-development, or production intermediate rather than as a finished active ingredient. Its suitability depends on identity, assay, water content, impurity profile, particle form, packaging, and the reaction or downstream application. At Maison Chemical, I support buyers by reviewing the required specification before discussing supply, documentation, packaging, and delivery arrangements.
4-Hydroxyphenylboronic acid is an organoboron compound in the aromatic boronic acid family. The boronic acid group is attached to a benzene ring, while the hydroxyl group is positioned at the 4-position relative to the boronic acid substituent. This para-substituted arrangement is also reflected in names such as 4-boronophenol and (4-hydroxyphenyl)boronic acid, although buyers should confirm that any synonym refers to the same CAS number.
| Property | Information |
|---|---|
| Product name | 4-Hydroxyphenylboronic acid |
| CAS Number | 71597-85-8 |
| Molecular formula | C6H7BO3 |
| Approximate molecular weight | 137.93 g/mol |
| Functional groups | Aryl boronic acid and phenolic hydroxyl |
The boronic acid group can react with suitable partners in palladium-catalyzed Suzuki–Miyaura coupling and related transformations. The phenolic hydroxyl group can also be retained, protected, or converted during subsequent synthesis, depending on the process design. Because the material contains two chemically useful functional sites, it can serve as a versatile intermediate for route development.
The principal synthetic role of 4-hydroxyphenylboronic acid is as an arylboronic acid coupling partner. In a Suzuki-type reaction, the arylboronic acid may be combined with an aryl or heteroaryl halide or a related electrophilic partner to form a new carbon–carbon bond. The precise catalyst, base, solvent, temperature, reaction time, and work-up conditions must be established for each substrate combination rather than assumed from the name of the reagent.
The para-hydroxy group provides an additional handle for making more complex molecules. Depending on the target structure, chemists may use the phenolic group in ether formation, esterification, protection, or other downstream transformations. I recommend confirming functional-group compatibility early, because protecting-group requirements and reaction sequence can influence yield, purification, and overall process cost.
I commonly position this material for applications where an aromatic boronic acid is needed together with a phenolic group. These applications can include medicinal chemistry libraries, pharmaceutical intermediate development, agrochemical research, specialty organic synthesis, and laboratory-scale process investigation. The compound may be used in route screening, analog preparation, or the synthesis of more advanced building blocks.
It is also relevant to research teams developing conjugated aromatic structures and functional materials, provided that the project has verified the required reaction compatibility. The presence of the phenolic group may support later molecular diversification, but it does not guarantee performance in every polymer, materials, or biological application. Buyers should define the exact target, reaction scale, and downstream quality requirements before selecting a commercial grade.
Commercial supply may be offered in different pack sizes and under different quality specifications, but those options should be treated as commercial configurations rather than universal properties of the chemical. A laboratory buyer may prioritize a high assay and small package, while a process-development buyer may require controlled impurity data, larger quantities, and consistent lot-to-lot documentation. For production use, the buyer should establish an agreed specification before purchase.
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I avoid treating a catalog description as a complete technical specification. Terms such as “high purity” or “research grade” can have different meanings between suppliers, so I encourage buyers to request measurable limits and the applicable test methods. If a project has regulatory, customer, or internal quality requirements, these should be communicated before quotation.
As with other laboratory and industrial chemicals, 4-hydroxyphenylboronic acid should be handled according to its current safety data sheet and the buyer’s site procedures. Personnel should use appropriate personal protective equipment, avoid generating dust, and work with suitable ventilation and containment. The specific hazard classification, transport status, and required controls should be confirmed from the applicable product documentation rather than inferred only from the chemical name.
Boronic acids can be sensitive to environmental conditions during storage, and moisture exposure may influence material condition or analytical results. I recommend keeping the container tightly closed, storing it in a cool and dry area appropriate for the product documentation, and limiting repeated opening. Buyers should also establish retest or shelf-life practices based on supplier data, internal stability studies, and the intended use.
When I evaluate a sourcing request, I first distinguish between a one-time research requirement and a repeat production requirement. The former may focus on availability, pack size, and delivery, while the latter usually requires stronger attention to batch consistency, change notification, documentation, and supply continuity. Neither approach is automatically better; the correct level of control depends on the project stage and risk profile.
Price alone is not a reliable selection criterion for an aromatic boronic acid. A lower unit price may be offset by unsuitable packaging, inconsistent assay, additional purification, or an uncertain lead time. I recommend comparing the total sourcing requirement, including documentation, quality review, logistics, and the cost of any failed or delayed experiments.
Maison Chemical supplies and exports organic boronic acid products for research, development, and commercial sourcing discussions. For 4-hydroxyphenylboronic acid CAS 71597-85-8, I can help clarify the requested quantity, target specification, packaging preference, destination, and intended application before preparing a quotation. This approach allows the commercial offer to reflect the buyer’s actual technical and logistical requirements.
My support can include product identity confirmation, specification alignment, document coordination, packaging discussion, and lead-time communication. Where the application is sensitive to moisture, impurities, or lot consistency, I recommend sharing those requirements at the inquiry stage. Availability, MOQ, and lead time should be confirmed for each order because they can vary according to quantity, production planning, and destination.
In direct terms, 4-hydroxyphenylboronic acid CAS 71597-85-8 is a bifunctional aromatic building block used primarily to introduce a hydroxy-substituted aryl unit into more complex molecules. Its boronic acid group supports coupling chemistry, while its phenolic group provides an additional site for downstream modification. The best product choice depends on the buyer’s reaction route, quality specification, quantity, and supply-chain requirements.
As a next step, I suggest sending Maison Chemical the required quantity, target assay, preferred packaging, destination, and application stage. I can then help confirm the appropriate commercial specification and provide current supply information. For a quotation or technical discussion, contact Maison Chemical with the CAS number 71597-85-8 so that the inquiry can be reviewed accurately.
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