Sorbitol oral solution - Cleveland Clinic

05 Jun.,2025

 

Sorbitol oral solution - Cleveland Clinic

What is this medication?

SORBITOL (SOR buh tol) treats occasional constipation. It works by increasing the amount of water your intestine absorbs. This softens the stool, making it easier to have a bowel movement. It also increases pressure, which prompts the muscles in your intestines to move stool. It belongs to a group of medications called laxatives.

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This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • Stomach or intestine problems
  • An unusual or allergic reaction to sorbitol, fructose, other medications, foods, dyes, or preservatives
  • Pregnant or trying to get pregnant
  • Breast-feeding

How should I use this medication?

Take this medication by mouth. Take it as directed on prescription label at the same time every day. Use a specially marked oral syringe, spoon, or dropper to measure each dose. Ask your pharmacist if you do not have one. Household spoons are not accurate. You can take it with or without food. If it upsets your stomach, take it with food.

This medication may also be used rectally with an enema. Follow the directions on the label. Wash your hands before and after use. Remove top from enema. Lubricate the tip of the bottle. Lie on your side with your lower leg straightened out and your upper leg bent forward towards your stomach. Lift upper buttock to expose the rectal area. Gently insert enema tip into the rectum. Squeeze the bottle until empty. Wait a few seconds before removing the bottle. Hold buttocks together for a few seconds. Remain lying down for about 15 minutes to avoid having the medication come out.

Talk to your care team about the use of this medication in children.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply. This medication is not for regular use, and should only be used as needed.

What may interact with this medication?

Interactions are not expected.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Tell your care team if your symptoms do not start to get better or if they get worse. Do not use this medication for longer than directed by your care team. This medication can be habit-forming. Long-term use can make your body depend on the laxative for regular bowel movements, damage the bowel, cause malnutrition, and cause problems with the amounts of water and salts in your body. If your constipation keeps returning, check with your care team.

Do not use with any other laxatives. Drink fluids as directed to prevent dehydration. See your care team right away if you do not have a bowel movement after using this medication.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

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  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

  • Diarrhea
  • Gas
  • Nausea
  • Upset stomach
  • Vomiting

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-.

Where should I keep my medication?

Keep out of the reach of children and pets.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Get rid of any unused medication after the expiration date.

To get rid of medications that are no longer needed or have expired:

  • Take the medications to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
  • If your cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, take the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Sorbitol | Baking Ingredients - BAKERpedia

Origin

Saccharin was the first commercially available artificial sweetener and was discovered in by Ira Remsen, a professor of chemistry with John Hopkins University. 2 Following the the commercial success of saccharin, new artificial sweeteners were introduced to the market, including aspartame, sucralose and sorbitol. While sorbitol was first isolated from berries by French chemists in , it was not commercially successful until saccharin established consumer demand for artificial sweeteners.

By the mid s, sorbitol was being industrially manufactured and was approved for use by the Federal Drug Administration (FDA) in .

Composition

Sorbitol appears as a white hygroscopic powder, as a crystalline powder or as flakes or granules. It is highly soluble in water and slightly soluble in ethanol. The standard preparation is to dissolve a weighed quantity of it in water to obtain a solution with a concentration of about 10.0 mg of per ml. 3

Commercial Production

Sorbitol has two-thirds the calories of sugar and, as mentioned earlier, is less sweet. It is poorly absorbed by the body, so it does not raise insulin levels as much as sugar does; nor does it promote tooth decay.

Sorbitol is  a glucose molecule with two hydrogens added. The two extra hydrogens are on either side of what used to be the double bond connecting the oxygen to the carbon, which is now a single bond.

It is industrially manufactured by the catalytic hydrogenation of the glucose produced from cornstarch. 4 In addition to its use as an artificial sweetener, sorbitol is also used as a humectant in cosmetics and toiletries and as a liquid vehicle, stabilizer and sweetener in pharmaceuticals. 5

Application

Sorbitol frequently comes in powder form and is used as a sweetener or moisture-stabilizing agent in the production of confectionery, baked goods and chocolate, among many other products. Its moisture-stabilizing action makes it a good choice for products that tend to become dry or harden, and it helps maintain freshness during storage. 6 Sorbitol can withstand high temperatures and it combines well with other food ingredients such as gelling agents, fats and sugars.

FDA Regulation

Sorbitol is certified as GRAS (generally recognized as safe) by the FDA. There are limits on the amount that can be used in food, and food containing an excess of 50 grams of sorbitol must be labeled with the statement: “Excess consumption may have a laxative effect.” For more information on the FDA guidelines for sorbitol use, please visit this FDA web page.

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References