4-Propylphenylboronic acid, also known as (4-propylphenyl)boronic acid, is an aryl boronic acid used mainly as a synthetic building block in organic and medicinal chemistry. Its CAS number is 134150-01-9, and its molecular formula is C9H13BO2, corresponding to a molecular weight of approximately 164.01 g/mol. I recommend evaluating this material primarily by identity, assay, impurity profile, packaging, documentation, and supply continuity rather than by price alone. At Maison Chemical, I support B2B buyers with product information and quotation guidance for project-specific sourcing.
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This guide is intended for pharmaceutical and agrochemical research teams, process chemists, custom synthesis companies, contract research organizations, and purchasing departments sourcing organic boronic acids. It is also useful for laboratories planning Suzuki-Miyaura coupling or related carbon-carbon bond-forming reactions. I focus here on practical selection and purchasing considerations rather than presenting this compound as a finished active pharmaceutical ingredient or a regulated formulation component.
Because commercial specifications can differ between suppliers and production lots, buyers should confirm the current certificate of analysis, analytical methods, storage instructions, and shipment documentation before placing an order. The information below describes the compound and common procurement logic in a conservative way. It should be combined with the buyer’s own experimental, quality, safety, and regulatory review.
4-Propylphenylboronic acid contains a boronic acid group attached to a benzene ring bearing a propyl substituent in the para position. The boronic acid functionality is the key reactive site, while the propyl group modifies the organic portion of the molecule and can influence steric, electronic, and solubility behavior in a reaction system. The compound is therefore best understood as a substituted aryl boronic acid rather than as a general-purpose solvent or catalyst.
| Parameter | Information |
|---|---|
| Product name | 4-Propylphenylboronic acid |
| CAS number | 134150-01-9 |
| Molecular formula | C9H13BO2 |
| Approximate molecular weight | 164.01 g/mol |
| Functional group | Aryl boronic acid |
The boronic acid group can participate in palladium-catalyzed Suzuki-Miyaura coupling with suitable aryl or heteroaryl halides and related electrophilic partners. In such reactions, the aryl group from the boronic acid is transferred to the coupling partner, creating a new carbon-carbon bond. Actual conversion depends on the reaction design, base, catalyst, solvent, temperature, concentration, substrate compatibility, and the quality of both reactants.
Boronic acids can also undergo oxidation and other transformations under appropriate chemical conditions. Their behavior may be affected by moisture, pH, heat, and the presence of reactive impurities. For this reason, I advise users to follow a validated laboratory procedure and to avoid assuming that one set of conditions will transfer directly to every substrate.
In medicinal chemistry, 4-propylphenylboronic acid may be used to introduce a para-propyl-substituted aryl fragment into a larger molecule. This can support the preparation of analogues for structure-activity relationship studies, lead optimization, and route scouting. The compound is a research intermediate and should not be described as a therapeutic ingredient unless it has been further processed and separately qualified for that purpose.
Organic boronic acids are also used in the preparation of specialty intermediates and candidate molecules for agrochemical research. The relevance of 4-propylphenylboronic acid depends on whether the target structure benefits from the specific para-propylphenyl group. Buyers should compare this compound with alternative substituted aryl boronic acids according to the required final structure, reaction selectivity, and available process data.
Process development teams may purchase small quantities for feasibility studies before considering larger project volumes. At this stage, consistent assay, reliable lot documentation, and reproducible packaging can be more important than a small difference in unit price. Once the route is confirmed, the buyer should reassess scale, impurity limits, retest expectations, and continuity of supply.
Suppliers may offer this material in different pack sizes and with different analytical specifications. A buyer should request a product specification and representative certificate of analysis rather than relying only on a catalog name. Common review items include appearance, identification, assay, water content, residual solvents, elemental impurities where relevant, and chromatographic impurity data.
Many research buyers use a purity requirement such as 98% or higher as an initial screening criterion, but the appropriate limit depends on the reaction and downstream use. I do not recommend treating a stated purity percentage as a guarantee of process performance without understanding the test method and impurity balance. For scale-up, the buyer may need additional information about batch consistency, analytical method validation, and change-control communication.
Before requesting a quotation, I suggest recording the target reaction, expected consumption, required purity, preferred pack size, delivery destination, and whether the material is for research or process development. This prevents suppliers from quoting an unsuitable grade or package. It also helps identify whether additional documentation is needed before import or internal quality approval.
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Compare suppliers using the same technical questions. Ask for the current specification, a recent lot-specific certificate where available, storage recommendations, and the proposed packaging configuration. If your chemistry is sensitive to water or oxidation, discuss those risks directly rather than assuming that standard packaging provides the level of protection your process requires.
Price should be evaluated together with quantity, lead time, shipping method, payment terms, documentation, and the possibility of repeat supply. MOQ and lead time are not universal properties of this chemical; they vary according to stock status, production planning, order size, destination, and logistics conditions. I recommend obtaining a written quotation that clearly separates product cost, packing, freight, and any applicable charges.
For an initial laboratory order, a small pack can reduce inventory exposure and confirm reaction performance. For a development or manufacturing program, buyers should discuss forecast volumes, batch reservation, production scheduling, and lot-to-lot consistency. A supplier that can communicate clearly about these points may reduce sourcing risk even when its initial price is not the lowest.
Handling should follow the supplier’s current safety data sheet and the buyer’s site procedures. Personnel should use appropriate laboratory controls, compatible gloves and eye protection, and suitable ventilation based on the risk assessment. I recommend minimizing unnecessary exposure to moisture, heat, contamination, and incompatible reagents, while keeping the container properly closed when not in use.
Storage conditions should be confirmed from the product documentation because the appropriate temperature, light protection, and shelf-life or retest approach may depend on packaging and supplier data. Do not infer a fixed shelf life without a stated manufacturer recommendation. Before use, inspect the container and material condition, and contact the supplier if the package is damaged or the material differs from the documented appearance.
One common mistake is ordering by name alone without checking the positional isomer. “Propylphenylboronic acid” can refer to different substitution patterns, and the para position is chemically significant. Another mistake is comparing assay values from different analytical methods as though they were directly equivalent.
Buyers also sometimes focus on a one-time laboratory price while overlooking repeat availability and documentation quality. A low-cost material may create delays if the required shipping papers, impurity information, or lot records are unavailable. Finally, it is risky to assume that a successful reaction with one lot proves that every future lot will behave identically without appropriate quality review.
At Maison Chemical, I approach 4-Propylphenylboronic acid sourcing as a technical B2B requirement rather than a simple catalog transaction. I can help buyers organize the key quotation details, including CAS number, required quantity, target specification, delivery location, packaging preference, and documentation needs. This information allows the supply discussion to remain precise and reduces avoidable clarification time.
For repeat projects, I also recommend discussing expected annual demand, preferred shipment schedule, quality requirements, and approval procedures at an early stage. Availability, MOQ, and lead time should be confirmed for each inquiry because they can change with inventory and production planning. Any commercial or technical commitment should be based on the current quotation and supporting documents provided for the specific order.
4-Propylphenylboronic acid CAS 134150-01-9 is a useful substituted aryl building block when the target synthesis requires a para-propylphenyl fragment. The best purchasing decision is not based on the chemical name or nominal price alone; it combines confirmed identity, fit-for-purpose quality data, suitable packaging, dependable documentation, and realistic delivery terms. I recommend starting with a clearly defined technical inquiry and reviewing the supplier’s current documents before approval.
For a quotation from Maison Chemical, send the required quantity, specification or purity target, destination, preferred package, intended use, and documentation requirements. I can then help determine the appropriate supply route and provide a current commercial response for your project. This structured approach supports faster laboratory evaluation and more reliable planning for later development volumes.
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